Melanotan 2
10 mg (lyophilized)
CAS #:
121062-08-6
LOT #:
258024
Purity:
99.78%
Endotoxin:
PASS
Cap colour is for illustration purposes only
Melanotan 2
10 mg (lyophilized)
+ $25 flat-rate shipping · free at $300+ · Interac e-Transfer ·
Volume pricing
Orders with confirmed payment before 2 PM EST on business days ship same day
About this compound
Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), engineered for enhanced metabolic stability and receptor binding affinity compared to the native linear peptide. It acts as a broad-spectrum melanocortin receptor agonist with activity at MC1R, MC3R, MC4R, and MC5R subtypes. Preclinical research has examined Melanotan II in the context of melanocortin receptor pharmacology, pigmentation biology, energy homeostasis, and central nervous system pathway modulation. Its structural cyclization confers resistance to proteolytic degradation, making it a useful tool compound in receptor binding and in vivo pharmacodynamic studies.
Storage and handling
Store at -20°C lyophilized, away from moisture and UV light. Keep vials sealed until use. Stable for 2+ years in a non-frost-free freezer.
Preclinical research references
Provided for informational context only. All cited studies involve preclinical or in vitro models. Results do not predict human safety or efficacy. These references do not constitute medical claims.
- Rodent models demonstrated that Melanotan II administration produced dose-dependent increases in eumelanin synthesis via MC1R activation in melanocyte cell cultures and in vivo skin pigmentation assays (Dorr et al., 1996)
- Mouse studies observed significant reductions in food intake and body weight in diet-induced obese models following MC4R-mediated hypothalamic signaling activation, independent of melanogenic effects (Koegler et al., 2001)
- Animal pharmacokinetic research confirmed extended plasma stability of the cyclic peptide compared to linear α-MSH analogues, supporting its utility as a long-acting melanocortin receptor probe in preclinical dose-response studies (Hadley et al., 1996)
- Rodent CNS studies demonstrated MC4R-mediated behavioral and autonomic responses following central and peripheral administration, informing research into melanocortin pathway involvement in energy regulation and neuroendocrine signaling (Wessells et al., 2003)
Shipping & returns
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Every batch independently tested for purity. COA on file and available before purchase.
FAQ — Melanotan 2
For research use only. Not for human or veterinary administration.