NAD+
1000 mg (lyophilized)
CAS #:
53-84-9
LOT #:
6026_0071
Purity:
99.93%
Endotoxin:
PASS
Cap colour is for illustration purposes only
NAD+
1000 mg (lyophilized)
+ $25 flat-rate shipping · free at $300+ · Interac e-Transfer ·
Volume pricing
Orders with confirmed payment before 2 PM EST on business days ship same day
About this compound
NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme present in all living cells, serving as a central mediator of redox chemistry and cellular energy metabolism. It functions as a hydride-ion carrier within the mitochondrial electron transport chain and acts as an essential substrate for NAD+-dependent enzymes, including sirtuins (SIRT1–SIRT7), poly(ADP-ribose) polymerases (PARPs), and cyclic ADP-ribose synthases (CD38/CD157). Preclinical research has extensively examined NAD+ in the context of mitochondrial biogenesis, DNA damage repair signaling, and the modulation of metabolic homeostasis across multiple tissue types. Age-associated decline in cellular NAD+ levels has been a key focus of longevity-oriented research, with animal models demonstrating that restoration of NAD+ pools can influence energy sensing pathways and mitochondrial function.
Key chemical details
- Formula weight
- 663.43 g/mol
- Molecular formula
- C21H27N7O14P2
- Common synonyms
- β-NAD+, DPN, Nadide, cozymase
Storage and handling
Store at -20°C lyophilized, away from moisture and UV light. Keep vials sealed until use. Stable for 2+ years in a non-frost-free freezer.
Preclinical research references
Provided for informational context only. All cited studies involve preclinical or in vitro models. Results do not predict human safety or efficacy. These references do not constitute medical claims.
- Rodent models demonstrated that NAD+ precursor supplementation restored age-related declines in tissue NAD+ concentrations and improved mitochondrial respiratory capacity in skeletal muscle (Yoshino et al., 2011)
- Mouse studies observed that NAD+ repletion activated SIRT1 and SIRT3 deacetylase activity, improving oxidative metabolism and insulin sensitivity markers in metabolically compromised cohorts (Cantó et al., 2012)
- Animal research showed systemic NAD+ supplementation reduced DNA damage biomarkers and extended healthspan metrics in aging rodent models via PARP-1 attenuation and sirtuin pathway upregulation (Gomes et al., 2013)
- Aged mouse models demonstrated that NAD+ restoration reversed age-associated pseudohypoxia in muscle tissue by modulating the SIRT1–HIF-1α axis, improving vascular density and exercise capacity (Gomes et al., 2013)
Shipping & returns
1–5 business days (5–7 for BC, NL and remote areas), Canada-wide tracked courier, double tamper-proof packaging.
All sales final. Damaged or incorrect orders must be reported within 24 hours with photos.
Every batch independently tested for purity. COA on file and available before purchase.
FAQ — NAD+ 1000 mg
For research use only. Not for human or veterinary administration.