TIRZ
20 mg (lyophilized)
Purity:
TBD
Cap colour is for illustration purposes only
TIRZ
20 mg (lyophilized)
+ $25 flat-rate shipping · free at $300+ · Interac e-Transfer ·
Volume pricing
About this compound
TIRZ is a synthetic dual-agonist peptide that simultaneously activates both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R). It is a 39-amino acid peptide with a C20 fatty diacid moiety enabling albumin binding and extended half-life. This 20 mg presentation provides a higher-concentration option for preclinical dose-response and pharmacokinetic research protocols. Currently in third-party testing — batch COA and confirmed purity will be posted once results clear.
Storage and handling
Store at -20°C lyophilized, away from moisture and UV light. Keep vials sealed until use. Stable for 2+ years in a non-frost-free freezer.
Preclinical research references
Provided for informational context only. All cited studies involve preclinical or in vitro models. Results do not predict human safety or efficacy. These references do not constitute medical claims.
- Diet-induced obese mouse models demonstrated that TIRZ produced significantly greater reductions in body weight and fat mass compared to selective GLP-1R agonists at equivalent doses, attributed to synergistic dual-receptor engagement (Coskun et al., 2022)
- Rodent metabolic studies observed that TIRZ normalized fasting glucose, improved insulin sensitivity, and reduced triglyceride levels in a dose-dependent manner across diabetic and obese animal models (Min et al., 2021)
- Primate pharmacokinetic studies confirmed extended plasma half-life and consistent receptor occupancy supporting extended dosing intervals, with favorable subcutaneous bioavailability profiles (Urva et al., 2022)
- Mouse energy expenditure studies showed TIRZ increased metabolic rate and reduced food intake through central GLP-1R and GIPR co-activation in hypothalamic circuits, independent of lean mass changes (Samms et al., 2021)
Shipping & returns
1–5 business days (5–7 for BC, NL and remote areas), Canada-wide tracked courier, double tamper-proof packaging.
All sales final. Damaged or incorrect orders must be reported within 24 hours with photos.
Every batch independently tested for purity. COA on file and available before purchase.
FAQ — TIRZ
For research use only. Not for human or veterinary administration.